Project Details

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Andrew Prayle

Contact Supervisor

Project area or title

Understanding the neurocognitive consequences of severe obstructive sleep apnoea in children


Obstructive Sleep Apnoea (OSA), which is growing in prevalence in the childhood population, is associated with sleep fragmentation, sleep deprivation and intermittent hypoxemia. OSA may be associated with reduced cognitive performance which impacts on scholastic achievement, but relationships between sleep parameters, daytime sleepiness, cognition and brain health in children are poorly understood.

This project involves sleep phenotyping (using polysomnography), cognitive profiling and brain imaging in children with OSA, to identify changes in brain haemodyamics or connectivity as mechanisms underlying cognitive alterations. This will form the basis for future studies looking at the impact of interventions for OSA on brain health.


Children, Young People & Perinatal Mental Health


University of Nottingham