Project Details

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Dr Matthew Apps

Project area or title

Computational approaches to the negative symptoms of psychosis


Current treatments for psychosis can help ameliorate positive symptoms such as delusions and hallucinations, but negative and cognitive elements of the phenotype are hard to treat and are important in determining long-term outcome. In this project, we want to develop work on decision-making in apathy and decision-making in healthy participants to a group in the early stages of psychosis. The project will employ computational modelling on two effort-based tasks, one behavioural and one during fMRI, and will examine how hidden states of fatigue fluctuate on a moment-to-moment basis on different timescales and reduce the willingness to exert effort for reward.


Severe Mental Health


University of Birmingham